Sources and method

How this site weighs evidence.

For stem cells, the source type matters almost as much as the content. Institutional pages, guidelines, official center profiles and consumer alerts carry a different weight than promotional copy or generic news coverage.

HierarchyInstitutional, clinical, basic
ChecksRoles, regulatory status, dates
GoalSeparate evidence, context and marketing

Method

Core editorial rules

Use institutional or official pages for regulation, roles, centers and program descriptions.

Keep basic research, preclinical work, clinical trials and standard care separate.

Avoid absolute rankings for doctors and institutions unless transparent comparable metrics exist.

State clearly when a source only documents public presence or outreach rather than clinical superiority.

Questions worth asking

  • Is the source institutional, scientific or commercial?
  • Is it discussing research, trials or established care?
  • Is the cellular product clearly defined?
  • Are limits, risks and regulatory status explicit?
  • Is the source recent enough for this field?

Source list

Main references used across the site

Source records

How a few key sources were weighted

NIH Stem Cell Information

Used as an institutional baseline for definitions, basic properties and high-level field framing.

Evidence type: institutional

Use in the site: definitions and conceptual structure

Latest update available: not clearly displayed on the reviewed page

FDA consumer information and alerts

Used for warnings on unapproved products, patient risk and the need to separate clinical trials from commercial offerings.

Evidence type: institutional/regulatory

Use in the site: caution, hype, regulatory framing

Latest update available: June 3, 2021 for the main FDA page reviewed

ISSCR Guidelines

Used to anchor the site to an international professional framework on stem cell research and clinical translation.

Evidence type: professional guideline

Use in the site: method, evidence hierarchy, caution in translation

Latest update available: should be re-checked periodically for revisions

Evidence hierarchy

What should weigh more when the question is clinical

Institutional level

FDA alerts, ISSCR guidelines and official hospital or university pages carry the most weight for regulatory status, program structure and documented roles.

Clinical level

Hospital transplant units and official clinical programs help document activity and indications, but they are not a substitute for comparative outcome evidence.

Basic science level

Laboratory research and explanatory articles are essential for understanding the field, but should not be confused with proof of routine clinical effectiveness.

Linked references

Two companion pages worth reading with this method page